Biochemical Analysis of Manganese Superoxide Dismutase Mutations

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Authors

Karlin, Molly
Hackett, Samantha
Richardson, Clara
Brabetz, Barbara

Issue Date

2016-04-04

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Learning Object
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en_US

Keywords

Mitochondria , Manganese Superoxide Dismutase , Hydrogen peroxide

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Abstract

Manganese Superoxide Dismutase, MnSOD, is a catalyst for antioxidant activity and provides a mechanism to convert highly active superoxide molecules radicals to a less toxic molecule in the form of hydrogen peroxide. This conversion allows initial protection from oxidative stress and the suppression of tumor forming activity.

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