Biochemical Analysis of Manganese Superoxide Dismutase Mutations

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Authors
Karlin, Molly
Hackett, Samantha
Richardson, Clara
Brabetz, Barbara
Issue Date
2016-04-04
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en_US
Keywords
Mitochondria , Manganese Superoxide Dismutase , Hydrogen peroxide
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Abstract
Manganese Superoxide Dismutase, MnSOD, is a catalyst for antioxidant activity and provides a mechanism to convert highly active superoxide molecules radicals to a less toxic molecule in the form of hydrogen peroxide. This conversion allows initial protection from oxidative stress and the suppression of tumor forming activity.
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