Effect of HXT2 on Oxidative Stress in Saccharomyces cerevisia

Abstract

Understanding the oxidative stress response of eukaryotic cells in relationship to reactive oxygen species (ROS) can open up many doors to understanding, and thus possibly curing, diseases caused by exposure to ROS such as cancer and neurodegenerative disorders. Previous studies have indicated hexose transport genes (HXTs) may significantly influence stress response of the eukaryotic organism Saccharomyces cerevisiae.

This study follows HXT2 mutants compared to normal strains of S. cerevisiae with the hypothesis that HXT2 mutants will show a significant decrease in growth when exposed to oxidative stress; varying results that show a possible correlation between HXT2 status and oxidative stress sensitivity, with further research needed for definitive support.