Review of The Use of 5-Fluorouracil as a Chemotherapy Drug to Treat Colorectal Adenocarcinoma

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Cincotta, Melissa
Wanits, Lyndsey
Whittaker, Jeremy

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2017

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en_US

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Colorectal Adenocarcinoma is a cancer isolated in the colon and rectum. It is the third most commonly diagnosed cancer in the United States[14].This cancer does not occur suddenly as it takes years to develop and tends to be caused by changes to the lining of the colon or rectum [4]. The p53 protein, that regulates the cell cycle to prevent mutations, is most commonly effected by colorectal adenocarcinoma by causing mismatch DNA repair sequence. [3]

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