In this poster presentation the focus will be on comparing perinatal HIV infections between industrialized and developing countries. The global awareness of HIV/AIDS has increased since it’s outbreak in the 1980’s. In most industrialized nations, such as the United States, the treatments and medications for treating HIV/AIDS and decreasing the transmission of the illness has been improving. HIV/AIDS is no longer seen as a death sentence but rather a chronic illness. Unfortunately even with all of the information and education on HIV/AIDS developing countries are not benefiting from the medical advancements due to the lack of financial means in those nations. The most important method of transmission that this article is focusing on is mother to child transmission (MTCT), which has been vastly decreased in the United States. With decreasing MTCT rates in Africa it will improve the overall quality of life in those developing countries. The existing research has been reviewed on MTCT in both industrialized and developing countries and it has been looked to see how to implement the methods from industrialized nations to decrease MTCT in developing nations in Africa.