Show simple item record

dc.contributor.authorBonnitto, Jalen, R.
dc.contributor.authorHameed, Nimra
dc.contributor.authorSkeen, Jourvonn
dc.contributor.authorDacius, Teddy, F. Jr.
dc.contributor.authorBarrera, Eddy
dc.contributor.authorRubi, Samantha
dc.contributor.authorKhairi, Eric
dc.contributor.authorIqbal, Asma
dc.contributor.authorLynch, Kirsten
dc.contributor.authorAhmed, Isra
dc.contributor.authorJose, Tokunbo, J.
dc.contributor.authorKaur, Sukhpreet
dc.date.accessioned2018-05-13T01:46:35Z
dc.date.available2018-05-13T01:46:35Z
dc.date.issued2018-04
dc.identifier.urihttp://hdl.handle.net/1951/70205
dc.descriptionStudent research from multiple departments examining the effects of lead exposure on rodent maternal pup retrieval and how it disrupts adolescent social-play.en_US
dc.description.abstractDevelopmental lead (Pb) exposure remains a valuable neurotoxicant rodent model of human environmentally induced cognitive disability, yet less is known about Pb-exposure on maternal pup care and its relationship to adolescent social-emotional behaviors such as social-play. Here we examined two developmental time-periods of Pb-exposure (i.e., Perinatal [PERI; pairing to day 22] and Postnatal [EPN; From Birth to day 22]), as well as the dose-response effects of Pb (i.e., 25 ppm, 150 ppm, and 1,000 ppm) administered through the drinking water. Maternal pup retrieval behaviors (i.e., latency across postnatal day (PND) 2-7) were correlated with adolescent social- play behaviors (i.e., attacks, pins, defenses, counters, and climbs) and compared against age- matched Control rats. The results showed that PERI and EPN maternal Pb-exposure increased pup * retrieval latencies from PND 5-7 when compared to Control rats. Additionally as a function of Pb- i dose, PERI maternal pup retrieval latencies increased from PNDs 5-7 with little within Pb dose- l effects. Adolescent social-play behaviors showed a sex-based increased difference in female rats engaging in more attacks, defenses, pins, counters, and climbs than males. PERI 150 ppm treated adolescent rats showed reduced female social-play behaviors, but were elevated in males. At PERI 1,000 ppm exposures, female social-play behaviors were similar to PBRI 150 ppm female rats, but interestingly males exhibited a 2- to 3-fold increase in social-play behaviors. These data suggest that environmental Pb-exposure may negatively influence maternal social care behaviors, thereby altering the natural trajectory of developmental social-emotional behaviors that emerge in adolescence with lifespan impacts. (SUNY-OW Faculty Development Grant).en_US
dc.description.sponsorshipLorenz S. Neuwirth; SUNY Old Westbury Department of Biology; Suny Old Westbury Department of Psychology; Neuroscience Research Institute, SUNY Old Westburyen_US
dc.language.isoen_USen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectlead exposureen_US
dc.subjectsocial playen_US
dc.subjectdevelopmenten_US
dc.titleDevelopmental lead exposure alters rodent maternal pup retrieval disrupting adolescent social playen_US
dc.typeLearning Objecten_US
dc.typePresentationen_US


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

  • Student Research [12]
    Select student presentations from the annual SUNY Undergraduate Research Conference (SURC)

Show simple item record

Attribution 3.0 United States
Except where otherwise noted, this item's license is described as Attribution 3.0 United States