Browsing SUNY Polytechnic Institute by Author "Shen, Bin"
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Large-scale ex vivo generation of human neutrophils from cord blood CD34+ cells
Jie, Zhenwang; Zhang, Yu; Wang, Chen; Shen, Bin; Guan, Xin; Ren, Zhihua; Ding, Xinxin; Dai, Wei; Jiang, Yongping (PLoS ONE, 2017-07-11)Conventional high-dose chemotherapy frequently leads to severe neutropenia, during which patients experience a high risk of infection. Although support care with donor’s neutrophils is possible this choice is largely ... -
Safety and efficacy of megakaryocytes induced from hematopoietic stem cells in murine and nonhuman primate models
Guan, Xin; Qin, Meng; Zhang, Yu; Wang, Yanan; Shen, Bin; Ren, Zhihua; Ding, Xinxin; Dai, Wei; Jiang, Yongping (Stem Cells Translational Medicine, 2016)Because of a lack of platelet supply and a U.S. Food and Drug Administration-approved platelet growth factor, megakaryocytes have emerged as an effective substitute for alleviating thrombocytopenia. Here, we report the ...