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dc.contributor.authorJiang, Yunru.
dc.contributor.authorYang, Siyuan.
dc.contributor.authorGuan, Jinming.
dc.contributor.authorMcMaster-Schuyler, Lynda, Dr.
dc.date.accessioned2015-05-04T14:52:13Z
dc.date.available2015-05-04T14:52:13Z
dc.date.issued2015-04
dc.identifier.urihttp://hdl.handle.net/1951/65550
dc.descriptionIn this research, RNAi constructs were first transformed in E. coli and C. elegans are fed E. coli bacteria containing relevant dsRNA for genes to be silenced. Phenotypic changes in offspring will be observed and documented to verify RNAi had been achieved.en_US
dc.description.abstractRNA interference (RNAi) is a biological process in which RNA molecules block gene expression, typically by causing the destruction of specific mRNA molecules. C. elegans is an excellent model system to study because many single gene mutations have been identified and the worms' transparency assist morphological observations. We are studying RNAi techniques by feeding E. coli to interrupt the dpy-11 and bli-1 genes in C. elegans, resulting in phenotype changes.en_US
dc.language.isoen_USen_US
dc.subject.lcshRNA -- Research -- New York (State)en_US
dc.subject.lcshRNA--Biotechnology.en_US
dc.subject.lcshCaenorhabditis elegans -- Genetics.en_US
dc.subject.lcshCaenorhabditis elegans -- Research -- New York (State)en_US
dc.subject.lcshWorms -- Research -- New York (State)en_US
dc.subject.lcshEscherichia coli.en_US
dc.subject.otherRNA Interferenceen_US
dc.subject.otherC. elegansen_US
dc.subject.otherdpy-11en_US
dc.subject.otherbli-1en_US
dc.titleInducing RNAi of dpy11 and bli-1 genes in C. elegansen_US
dc.typePresentationen_US


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