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dc.contributor.authorAwomolo, Adeola
dc.date.accessioned2010-07-29T17:36:01Z
dc.date.available2010-07-29T17:36:01Z
dc.date.issued2010-07-29T17:36:01Z
dc.identifier.urihttp://hdl.handle.net/1951/48145
dc.descriptionPowerpoint slides describing a research project prepared for the Presidential Scholars Presentation Series, April 29, 2010. Advisor: Fadi Bou-Abdallah, Chemistry Department.en
dc.description.abstractThe importance of iron in living systems cannot be overestimated. If iron is not managed efficiently, the aftermath could be catastrophic. My research project focused on understanding the structure and function of a major iron binding and storage protein called “Ferritin”. Because of its ubiquitous presence and involvement in iron balance, ferritin plays a key role in a multitude of human iron-related diseases such as hemochromatosis, anemia and a number of cancers and neurodegenerative diseases. These iron-related problems are mainly caused by the 'corrosive chemistry' of iron and oxygen. The World Health Organization estimates some 80% of the World's population (some five billion plus people) are afflicted with iron-related diseases. Thus, investigating the iron uptake and release by ferritin is a crucial step to understanding the underlying reasons of these diseases at the molecular level. The ultimate goal is to design drug molecules that would extract or deliver iron efficiently and thus treat these devastating diseases.en
dc.description.sponsorshipChemistry Department. Fadi Bou-Abdallah, Advisor. Presidential Scholars Program.en
dc.language.isoen_USen
dc.subjectbiochemistryen
dc.subjectIron overloaden
dc.subjectIron storageen
dc.subjectFree radical formationen
dc.subjectTransferrinen
dc.subjectFerroxidase Centeren
dc.subjectHuHFen
dc.subjectEcftnAen
dc.titleHemochromatosis and Ferritinen
dc.typePresentationen


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