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  • Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS 

    Krug, Lisa; Chatterjee, Nabanita; Borges-Monroy, Rebeca; Hearn, Stephen; Liao, Wen-Wei; Morrill, Kathleen; Prazak, Lisa; Rozhkov, Nikolay; Theodorou, Delphine; Hammell, Molly; Dubnau, Josh (PLOS Genetics, 2017-03-16)
    Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are two incurable neurodegenerative disorders that exist on a symptomological spectrum and share both genetic underpinnings and pathophysiological ...