Browsing by Author "Zhang, Yu"
Now showing items 1-4 of 4
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Design, Synthesis and Biological Evaluation of Novel Curcumin Analogues as Inhibitors of Matrix Metalloproteinases and Pro-inflammatory Cytokines
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Dec-12)There are two principal reasons why we age: 1) the toxicity of oxygen species; 2) the continuous degradation of collagen by groups of enzymes such as the matrix metalloproteinases (MMPs). The MMPs are a group of more than ... -
Growth Mechanisms and Defect Structures of B12As2 Epilayers
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-May-11)As a member of icosahedra boride family of materials, icosahedral boron arsenide (B<sub>12</sub>As<sub>2</sub>), with a wide band gap of 3.2eV at room temperature, possesses extraordinary resistance against radiation damage ... -
Large-scale ex vivo generation of human neutrophils from cord blood CD34+ cells
(PLoS ONE, 2017-07-11)Conventional high-dose chemotherapy frequently leads to severe neutropenia, during which patients experience a high risk of infection. Although support care with donor’s neutrophils is possible this choice is largely ... -
Safety and efficacy of megakaryocytes induced from hematopoietic stem cells in murine and nonhuman primate models
(Stem Cells Translational Medicine, 2016)Because of a lack of platelet supply and a U.S. Food and Drug Administration-approved platelet growth factor, megakaryocytes have emerged as an effective substitute for alleviating thrombocytopenia. Here, we report the ...
