Browsing by Author "Hanel, Walter George"
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Two p53 mutants display differential gain-of-function effects on tumorigenesis in vivo
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-12)p53 is a transcription factor which promotes cell cycle arrest, DNA damage repair, and apoptosis in the presence of DNA damage or oncogenic signaling. It is mutated in more than half of all human cancers demonstrating ...
