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Now showing items 1-20 of 24990
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Statesman V. 31, n. 18
(State University of New York at Stony Brook., /1987/1987) -
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The Effect of chr16p11.2 Microdeletions and Microduplications on Gene Expression in Autism Spectrum Disorders and Schizophrenia.
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The number of rare variants found to be associated with multiple psychiatric disorders is growing. One such locus is a recurrent ~600kb copy number variant (CNV) at 16p11.2, occurring in approximately 1% of autism and 0.3% ... -
A Nuanced Perspective of Sexual Orientation and its Relationship with Well-being: Differentiating Sexual and Non-sexual Attractions in Heterosexual and Sexual Minority Women and Men
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Research has demonstrated that violating the norm of heterosexuality by endorsing a sexual minority identity is associated with poorer psychological well-being. Such studies have failed to take into account the multifaceted ... -
Modeling the tagged neutron technique for the identification of Unexploded Ordnance
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Abstract of the ThesisModeling the tagged neutron technique for the identification of Unexploded OrdnancebyYuanyuan WangMaster of ScienceinMechanical EngineeringStony Brook University2010This research is a collaboration ... -
Design, Synthesis and Biological Evaluation of Novel Tumor-targeting Taxane-based Drug Delivery Systems
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Cancer continues to be a leading cause of death in the U.S. after heart disease and has become the leading cause of death for people younger than 85. Cancer chemotherapy relies on the hypothesis that rapidly proliferating ... -
Expression and function of REST in oligodendrocyte lineage cells
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The RE1-silencing transcription factor (REST) regulates the expression of neural specific genes by acting as a transcriptional repressor in non-neuronal cells. REST binds to repressor elements (RE1s) in the DNA and recruits ... -
Assessing and accommodating addressees' needs: The role of speakers' prior expectations and addressees' feedback
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)In dialogue, a conversational partner's behavior is not solely the product of one individual mind, but instead reflects a process of mutual coordination between both conversational partners. This project investigates how ... -
Algorithms for Optimizing Multiple Routes Through Constrained Geometric Domain
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)We study optimization problems associated with routing multiple moving objects through a two- or three-dimensional geometric domain. We focus primarily on trajectories for moving disks, which can be used to model motion ... -
Orbifold Degeneration of Conformally Compact Einstein Metrics
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)In his investigation of the Dirichlet problem for conformally compact Einstein metrics, Anderson showed that there are (at most) three possibilities for the behavior, under subsequences, of a sequence of conformally compact ... -
Application of Transition Metal-Catalyzed Reactions in the Synthesis of N- Heterocyclic Natural Products
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Metal-catalyzed carbon-carbon bond forming reactions have become one of the most powerful synthetic reactions of the modern organic chemistry reaction arsenal. These reactions have allowed for easier access to more complex ... -
Strong Field Control of Multilevel Quantum Systems
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)In this thesis, we present work on coherent control of multilevelquantum systems in the strong field limit using shaped ultrafastlaser pulses. In recent years there have been numerous multiphotonabsorption experiments in ... -
Collaborative and Heterogeneous Signal Processing Methodology for Mobile Sensor Based Applications
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Multiple object tracking and association are key capabilities in mobile sensor based applications (i.e., a large scale flexible surveillance system and multiple robots application system). Such systems track and identify ... -
Experimental Verification of Nonlinear System Model Parameter Identification Based On Trajectory Pattern Method
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The purpose of this thesis was to verify the Trajectory Pattern Method (TPM) based nonlinear system model parameter identification method for a two degrees of freedom closed loop planar robotic manipulator. The systematic ... -
Role of Serotonin (5-HT) in Hypoxic and Hypercapnic Ventilatory Responses
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Breathing is fundamental to life, and responding appropriately to hypercapnic and hypoxic conditions is essential to survival. Abberant respiratory behavior is a feature of a wide variety of clinical conditions, and appears ... -
Tissue Plasminogen Activator & Plasminogen System in Chondroitinase-mediated Axonal Plasticity
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Following Spinal Cord Injury (SCI) the injured neurons are unable to regenerate as they face an inhibitory external environment and the lack of guidance cues for direct regrowth of severed axons. A component of the inhibitory ... -
The roles of Mek1 and cohesins in suppressing meiotic intersister double-strand break repair
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Reciprocal exchange between homologs, in combination with sister chromatid cohesion, promotes proper segregation of homologs at Meiosis I. Missegregation of chromosomes during meiosis causes abnormal chromosome numbers in ... -
Suppressor of Cytokine Signaling 3 Blocks Breast Tumor Kinase Activation of STAT3 Transcription Factor
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The Signal Transducers and Activators of Transcription (STATs) are a family of transcription factors that play important roles in cytokine signaling. Following cytokine stimulation they are tyrosine phosphorylated by ... -
Non-recurrent dynamics in the exponential family
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)This dissertation deals with the dynamics of non-recurrent parameters in the exponential family $\{e^z+c\}$. One of the main open problems in one-dimensional complex dynamics is whether hyperbolic parameters are dense;this ... -
Static Disassembly Of Stripped Binaries
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Disassembly of binaries plays an important role in computer security.Tools for binary analysis and reverse engineering rely heavily on staticdisassembly. Current disassemblers are not able to reliably disassembleexecutables ...
