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Now showing items 21-40 of 31349
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Probing the Mesolimbic Dopamine Reward System: A Common Neurocircuitry in Substance Abuse and Schizophrenia
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Substance abuse is more prevalent among patients with schizophrenia than in the general population. Interestingly, the pathophysiology of schizophrenia is thought to share many overlapping features with drug addiction, ... -
A Multi-class Classification using Ensembles of Multinomial Logistic Regression Models
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)This research proposes a method for multi-way classification problems using ensembles of multinomial logistic regression models. A multinomial logit model is used as a base classifier in ensembles from random partitions ... -
A Home Divided: A Post-National Approach to Family, Gender and Region in Modern Galician Narrative
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)By focusing on the case of Galicia, A Home Divided represents an attempt to understand the multiple linguistic and gendered subjectivities that are enclosed within and excluded from larger regional/national Iberian identities. ... -
Identification of L1334, a unique glycopeptidolipid isolated from a M. smegmatis MSMEG1604 mutant and functional characterization of Rv3409c from M. tuberculosis
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)M. tuberculosis has a cholesterol oxidizing activity that initiates sterol metabolism, which may be related to its virulence. Rv3409c of M. tuberculosis H37Rv was annotated as a putative cholesterol oxidase, an enzyme that ... -
Role of Serotonin (5-HT) in Hypoxic and Hypercapnic Ventilatory Responses
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Breathing is fundamental to life, and responding appropriately to hypercapnic and hypoxic conditions is essential to survival. Abberant respiratory behavior is a feature of a wide variety of clinical conditions, and appears ... -
Static Disassembly Of Stripped Binaries
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Disassembly of binaries plays an important role in computer security.Tools for binary analysis and reverse engineering rely heavily on staticdisassembly. Current disassemblers are not able to reliably disassembleexecutables ... -
Tissue Plasminogen Activator & Plasminogen System in Chondroitinase-mediated Axonal Plasticity
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Following Spinal Cord Injury (SCI) the injured neurons are unable to regenerate as they face an inhibitory external environment and the lack of guidance cues for direct regrowth of severed axons. A component of the inhibitory ... -
Non-recurrent dynamics in the exponential family
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)This dissertation deals with the dynamics of non-recurrent parameters in the exponential family $\{e^z+c\}$. One of the main open problems in one-dimensional complex dynamics is whether hyperbolic parameters are dense;this ... -
Global Genetic Stock Structure of the Copper (Carcharhinus brachyurus) and Dusky Sharks (Carcharhinus obscurus): Interspecific Comparisons and Implications for Management
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Genetic stock structure information is needed to help delineate management units and monitor trade in sharks, many of which are heavily exploited and declining. Among these, the copper (Carcharhinus brachyurus) and dusky ... -
Application of Transition Metal-Catalyzed Reactions in the Synthesis of N- Heterocyclic Natural Products
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Metal-catalyzed carbon-carbon bond forming reactions have become one of the most powerful synthetic reactions of the modern organic chemistry reaction arsenal. These reactions have allowed for easier access to more complex ... -
Collaborative and Heterogeneous Signal Processing Methodology for Mobile Sensor Based Applications
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Multiple object tracking and association are key capabilities in mobile sensor based applications (i.e., a large scale flexible surveillance system and multiple robots application system). Such systems track and identify ... -
The roles of Mek1 and cohesins in suppressing meiotic intersister double-strand break repair
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Reciprocal exchange between homologs, in combination with sister chromatid cohesion, promotes proper segregation of homologs at Meiosis I. Missegregation of chromosomes during meiosis causes abnormal chromosome numbers in ... -
Experimental Verification of Nonlinear System Model Parameter Identification Based On Trajectory Pattern Method
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The purpose of this thesis was to verify the Trajectory Pattern Method (TPM) based nonlinear system model parameter identification method for a two degrees of freedom closed loop planar robotic manipulator. The systematic ... -
Suppressor of Cytokine Signaling 3 Blocks Breast Tumor Kinase Activation of STAT3 Transcription Factor
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The Signal Transducers and Activators of Transcription (STATs) are a family of transcription factors that play important roles in cytokine signaling. Following cytokine stimulation they are tyrosine phosphorylated by ... -
Design, Synthesis and Biological Evaluation of Novel Tumor-targeting Taxane-based Drug Delivery Systems
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)Cancer continues to be a leading cause of death in the U.S. after heart disease and has become the leading cause of death for people younger than 85. Cancer chemotherapy relies on the hypothesis that rapidly proliferating ... -
La Po tica Material del Exilio en el Cine Latinoamericano y Espa¤ol
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)This dissertation is the result of a study of selected Latin American and Spanish films that deal with the topic of exile. Following a thematic and stylistic criterion closely related to Hamid Naficy's notion of"accented ... -
Algorithms for Optimizing Multiple Routes Through Constrained Geometric Domain
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)We study optimization problems associated with routing multiple moving objects through a two- or three-dimensional geometric domain. We focus primarily on trajectories for moving disks, which can be used to model motion ... -
Orbifold Degeneration of Conformally Compact Einstein Metrics
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)In his investigation of the Dirichlet problem for conformally compact Einstein metrics, Anderson showed that there are (at most) three possibilities for the behavior, under subsequences, of a sequence of conformally compact ... -
Expression and function of REST in oligodendrocyte lineage cells
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)The RE1-silencing transcription factor (REST) regulates the expression of neural specific genes by acting as a transcriptional repressor in non-neuronal cells. REST binds to repressor elements (RE1s) in the DNA and recruits ... -
Strong Field Control of Multilevel Quantum Systems
(The Graduate School, Stony Brook University: Stony Brook, NY., 1-Aug-10)In this thesis, we present work on coherent control of multilevelquantum systems in the strong field limit using shaped ultrafastlaser pulses. In recent years there have been numerous multiphotonabsorption experiments in ...
